Objective To retrieve,evaluate and summarize the best evidence of self-management of lymphedema of breast cancer patients’,and to provide references for education and evaluation of self-management of patients. Methods We searched relevant guideline networks and association websites,as well as PubMed,Web of Science,Embase,CINAHL,CNKI,VIP,Wanfang,CBM and other databases to collect relevant guidelines,expert consensuses,best practices and recommended practices related to self-management of lymphedema in breast cancer patients published from January 1,2011 to May 31,2021. 2 researchers evaluated the quality of various literature,and extracted relevant evidence from the included literature. Results A total of 24 articles were included,including 7 guidelines,6 expert consensuses,3 best practices and 8 recommended practices. Finally,28 pieces of best evidence including 8 dimensions were summarized,namely learning about lymphedema,exercise,maintaining a healthy weight,protecting the affected limb,promoting lymphatic circulation,self-monitoring,psychological adjustment and role adaptation. Conclusion This study summarized the best evidence of breast cancer patients’ self-management of lymphedema,which can provide references for medical staffs to conduct self-management guidance for patients and dynamically evaluate their self-management status,so as to effectively prevent or control lymphedema.